摘要
目的评价X线对肺表面活性物质（PS）固尔苏治疗肺透明膜病（HMD）的疗效监测。方法回顾确诊为Ⅲ～Ⅳ级HMD、应用PS治疗的早产儿21例病例，采用用药后1／2h、6h、24h、48h、5d胸片观察。结果用药后1／2h胸片双肺透亮度即有改善15例；肺部表现进行性改善，较前次胸片好转16例；病变无改变或进展5例，其中并发肺出血1例，出现气漏3例；伴有肺部炎症样改变3例；动脉导管开放（PDA）11例。结论使用PS治疗后胸片动态观察能对Ⅲ～Ⅳ级HMD病变转归作出正确判断，短期复查能及时发现HMD并发症。
Objective To analyze the characteristics of the dynamic changes of the radiological X-ray images in chest after applying a pulmonary surfactant（PS） named curosurf to hyaline membrane disease in grade Ⅲ～Ⅳ of the premature lungs,and to study the clinical values of the follow-ups with chest films after applying PS to evaluate its effects and to detect the complications in chest. Methods To review the definite cases of HMD in grade Ⅲ～Ⅳ with final clinical and radiological diagnosis so as to analyze the radiological image manifestations in chest after applying PS to the premature lungs for half an hour, for 6 hours, for 24 hours, for 48 hours and for 5 days. Results Shortly after the application of PS,according to the chest films,just half an hour later, 15 cases improved their degrees of the transmittance of the two lungs; 16 cases progressively ameliorated their manifestations in chest, taking the turn for the better than the previous images;5 cases had no improvement, among which 1 developed a complication of pulmonary hemorrhage, and 3 developed pulmonary air leakage; 3 cases accompanied with pulmonary inflammation-like lesions; 11 cases presented patent arterial ducts（PDA）. Generally speaking, the X-ray image manifestation was the same as the clinical symptoms. Conclusion A dynamic observation of the X-ray films in chest after the application of PS is able to make a correct judgement of the lesions of HMD in grade Ⅲ～Ⅳ ,and can promptly detect its complications if taking a short-term review.
出处
《中国基层医药》
CAS
2008年第4期574-575,707,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
透明膜病
放射摄影术
胸部
Hyaline membrane disease
Radiography, thoracic
