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儿童哮喘患儿血清IL-18与IL-13水平变化的研究 被引量：1

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摘要 目的探讨IL-18，IL-13等细胞因子在儿科哮喘发病中的作用机制。方法分哮喘急性发作组42例（其中急性发作轻-中度16例，重度及危重度26例），哮喘缓解组37例，对照组30例，采用ELISA方法检测其血清IL-18，IL-13水平。结果哮喘患儿急性发作期、缓解期与对照组比较，IL-18，IL-13增高，差异有统计学意义（均P〈0、01），随着哮喘患儿严重程度增加其血清IL-18，IL-13水平也相应增高，差异有统计学意义（P〈0、05）。结论IL-18，IL-13与儿童哮喘发病机制有关。
作者 范楚平 何庆南 彭华保 张碧清
机构地区 湖南省郴州市第一人民医院儿童内科I区 中南大学湘雅二医院
出处 《中国医师杂志》 CAS 2008年第5期676-677,共2页 Journal of Chinese Physician
关键词 哮喘 白细胞介素18 白细胞介素13
分类号 R725.6 [医药卫生—儿科]
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共引文献58

同被引文献9

  • 1黄磊,魏明发,冯杰雄,袁继炎,王小林.胆道闭锁汇管区炎性细胞浸润及其细胞因子的表达研究[J].中华小儿外科杂志,2007,28(11):575-578. 被引量：3
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  • 9沈桢(综述),郑珊(审校).儿童肝移植的远期预后[J].中华小儿外科杂志,2010(2):145-147. 被引量：5

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中国医师杂志
2008年 第5期

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