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沙门菌的耐药性机制研究进展 被引量：14

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摘要 自上世纪末期沙门菌耐药菌株的逐渐增多,特别是多重耐药菌株的出现,给沙门菌病治疗带来了极大困难,成为公共健康的一大威胁。目前关于沙门菌耐药性机制,国内外已有较多研究报道,主要集中于以下几个方面:①拓扑异构酶基因的突变;②抗菌药物摄取或累积量降低;③可转移遗传元件介导的耐药性机制;④质粒介导的喹诺酮类药物耐药性(Plasmid-mediated quinolone resistance,PMQR)。本文着重综述上述几种沙门菌耐药性机制研究进展。
作者 邱少富 端青
机构地区 军事医学科学院微生物流行病研究所病原微生物生物安全国家重点实验室
出处 《微生物学免疫学进展》 2008年第2期55-59,共5页 Progress In Microbiology and Immunology
关键词 沙门菌 多重耐药 耐药性机制
分类号 R378.2 [医药卫生—病原生物学]
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参考文献25

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微生物学免疫学进展
2008年 第2期

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