期刊文献+

炎性标志物与动脉粥样硬化 被引量:2

Inflammatory Biomarkers and Atherosclerosis
下载PDF
导出
摘要 炎症是动脉硬化发病的重要环节,在促进动脉粥样硬化斑块形成、破裂,以及随后导致的心血管疾病的临床症状中扮演着重要的角色。这些炎性标志物既可以作为证实患者患有冠状动脉疾病的诊断依据,又可以进一步帮助证实患者所处的危险程度。现就与动脉粥样硬化密切相关的炎性标志物的分类、功能及其在冠状动脉疾病发生过程中的作用进行综述。 Inflammation is a key link in the genesis of atherosclerosis.,it plays a pivotal role in promoting the genesis and rapture of atherosclerotic plaque and then leading to clinical syndromes of cardiovascular disease.These inflammatory biomarkers not only can be considered to be diagnostic reference for the identification of patients with coronary diseases,but also can help us to furtherly identify the dangerous degree of patients.This article reviews biomarkers closely related to atherosclerosis about their classification,function and their effect played in the development of coronary atherosclerosis.
作者 钟芝茵 周喆
出处 《医学综述》 2008年第11期1627-1629,共3页 Medical Recapitulate
关键词 动脉粥样硬化 炎症 标志物 Atherosclerosis Inflammation Biomarkers
  • 相关文献

参考文献20

  • 1Libby P, Ridker PM. Inflammation and atherothrombosis :from population biology and bench research to clinical practice [ J ]. J Am College Cardiol,2006,48 (9) :33-46.
  • 2OHara RM Jr, Benoit SE, Groves CJ. Cell-surface and cytokine biomarkers in autoimmune and inflammatory diseases[ J ]. Drug Discov Today ,2006,11 (7/8) :342-347.
  • 3Kinlay S, Selwyn AP. Effects of statins on inflammation in patients with acute and chroniccoronary syndromes [ J ]. Am J Cardiol, 2003,91 (4A) :9-13.
  • 4Fichtlscherer S, Heeschen C, Zeiher AM. Inflammatory markers and coronary artery disease [ J ]. Curr Opin Pharmacol, 2004,4 ( 2 ) : 124-131.
  • 5Antonin M, Gotto AM Jr. Role of C-reactive protein in coronary risk reduction : focus on primary prevention [ J ]. Am J Cardiol,2007,99 (5) :718-725.
  • 6Ahmed MH. Cardiovcascular disease : is C-reactive protein the bad guy? [ J]. Diabetes Res Clin Pract ,2007,76(3 ) :472-473.
  • 7Dabrowski R, Wawron W, Kostro K. Changes in CRP, SAA and haptoglobin produced in response to ovariohysterectomy in healthy bitches and those with pyometra [ J ]. Theriogenology, 2007, 67 (2) :321-327.
  • 8Ogasawara K, Mashiba S, Wada Y, et al. A serum amyloid A and LDL complex as a new prognostic marker in stable coronary artery disease[ J ]. Atherosclerosis,2004,174 (2) :349-356.
  • 9Maurel S,Hamon B,Taillandier J,et al. Prognostic value of serum interleukin-6 (IL-6) levels in long term care [ J]. Arch Gerontol Geriatr ,2007,45 ( 1 ) : 65-71.
  • 10Paik JK, Kim OY, Kch SJ, et al. Additive effect of interleukin-6 and C-reaction protein (CRP) single nucleotide polymorphism on serum CRP concentration and other cardiovascular risk factors [ J ]. Clin Chim Acta,2007,380(1/2) :68-74.

同被引文献15

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部