摘要
目的观察脑梗死(CI)急性期血清超敏C反应蛋白(hs-CRP)、IL-6、IL-18、及外周血白细胞总数、中性粒细胞百分比变化。方法对182例脑梗死患者分别抽静脉血统计白细胞总数、中性粒细胞百分比,测定血清hs-CRP、IL-6、IL-18的含量。结果脑梗死组白细胞总数、中性粒细胞百分比显著增高(P<0.01),hs-CRP、IL-6、IL-18水平明显高于健康组(P<0.01)。结论测定急性脑梗阻死患者血清hs-CRP、IL-6、IL-18并观察外周血白细胞的变化,对急性脑梗死患者有较好的诊断价值,是评估治疗、病性轻重的很好指标。
[Objective] To observe the varieties of serum CRP, cytokine levels and peripheral leukocyte count in acute cerebral infarction patients. [Metheds] Serum levels of hs-CRP, IL-6, IL-18, perpheral leukocyte count and the percentage of neutrophilc granulocyte were determined in one hundred and eighty two patients with acute cerebral infarction and one hundred control. [Rusults] The leukocyte count and the percent of neutrophilc granulocyte in infarction patients increased obviously（P 〈0.01）. Serum levels of hs-CRP, IL-6, IL-18 were signficantly higher than those of controls（P 〈0.01）. [Conclusion] Determination of serum hs-CRP, IL-6, IL-18 contents in patients with acute cerebral is of diagnostic and prognostic value, and can be estimated by leukocyte count and the percentage of neutrophiles, in acute cerebral infarction patients.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2008年第10期1423-1425,共3页
China Journal of Modern Medicine
