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膝关节骨性关节炎放射治疗6例初探

Preliminary Inquire into Six Cases of Knee Osteoarthritis Radiotherapy
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摘要 目的:观察直线加速器放射治疗膝关节骨性关节炎临床疗效和安全性,以期为骨性关节炎提供新的治疗手段。方法:放射治疗采用直线加速器6MV-X线,分次剂量100cGy,隔日1次,3次/周,连续6次,总剂量DT600cGy,2~3周完成。结果:放射治疗结束时6例患者休息痛、触痛均消失;5例中度疼痛患者,2例转为轻度疼痛,3例疼痛消失;2例关节肿胀患者均有减轻。完全缓解率50%(3/6),部分缓解率50%(3/6),总有效率10096。所有病例未见不良反应。结论:放射治疗骨性关节炎起效也比较快,却无长期口服药物的副作用,花费少,能极好地替代常规治疗,一些患者也可避免了手术治疗。由于观察时间短,未见不良反应。 Objective: To observethe clinical efficacy and safety of linear accelerator radiation treatment of knee osteoarthritis, with a view to find a new way to treat osteoarthritis. Methods: Using linear accelerator 6MV X - ray for radiation therapy , dose 100cGy, qod, 3times/week, consecutive six times, the total dose DT600cGy, 2-3weeeks to complete. Results:At the end of radiation therapy , 6 cases rest pain and tenderness disappeared, 5 cases with moderate pain, and 2 cases with mild pain, 3cases of pain disappeared, 2 patients have joint swelling ease. Complete remission rate of 50 % (3/6phase), partial remission rate of 50 % (3/6phase), the total efficiency of 100 %. All patients have no adverse reactions. Conclusions: Radiation treatment of osteoarthritis onset is relatively fast, but no long - term side effects of oral drugs and spend less, can be an excellent alternative to conventional treatment, some patients can avoid surgery. Due to the short duration, no adverse reactions.
出处 《内蒙古医学杂志》 2008年第5期557-558,共2页 Inner Mongolia Medical Journal
关键词 骨性关节炎 膝关节 放射治疗 Osteoar thritis Knee Radiotherapy
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参考文献3

  • 1Trott KR, Kamprad F. Radiobiological mechanisms of anti - inflammatory radiotherapy [ J ]. Radiother Oncol, 1999, 51 : 197 - 203.
  • 2Hildebrandt G, Seed MP, Freemanfle CN, et al. Mechanisms of the anti- inflammatory activity of low - dose radiation therapy [ J ]. Int. J. Radiat. Biol, 1998, 74:367 - 378.
  • 3Homikiewytsch T. Physikalisch - chemische und histochemische Untersuchungen ueber die Wirkung yon Roentgenstrahlen [ J ]. Strahlenther Onkol, 1952, 86 : 175 - 207.

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