摘要
目的探讨卵巢颗粒细胞瘤的临床表现、病理特点、分期、治疗方法等与预后和复发的关系。方法对我院1990年1月—2001年12月收住经病理诊断为卵巢颗粒细胞瘤的26例患者的临床资料进行回顾性分析研究,按就诊时间分为A组(1995年前就诊者)和B组(1995年以后就诊者)。分析卵巢颗粒细胞瘤患者的年龄、临床分期、病理因素、治疗方法等因素与预后的关系。结果卵巢颗粒细胞瘤患者的5年和10年存活率随临床分期的增加而降低;原肿瘤组织分化程度不同,5年和10年存活率差异有统计学意义;≥40岁和<40岁患者5、10年存活率差异无统计学意义(P>0.05);临床Ⅰ期患者应用不同的治疗方法对存活率无明显影响(P>0.05)。结论卵巢颗粒细胞瘤的临床分期及细胞核异型性及高分裂相是影响其预后的重要相关因素。
Objective To study the effect of clinical and pathologic factors, staging, cure method on prognosis and recurrence for granulosa cell tumor of the ovary. Methods The clinical records of 26 patients with granulosa cell tumors of the ovary enrolled between 1990 and 2001 were reviewed. The relationship between age、 stage,mitosis and the adjuvant therapy for early stage （stage I） were analyzed retrospectively. Patients with recurrent tumors were compared with patients who remained healthy. Patients with early recurring tumors were compared with late recurring tumors. Results The clinical stage, proliferation could significantly influenced the 5 - year survival rate and 10- year survival rate in patients with ovarian granulose cell tumor. Conclusion Tumor stage and mitotic rate are the clinical and pathologic prognostic factors in granulosa cell tumor. It is difficult to predict late recurrences using these clinical and pathologic parameters.
出处
《宁夏医学院学报》
2008年第3期330-332,共3页
Journal of Ningxia Medical College
关键词
卵巢肿瘤
颗粒细胞瘤
临床分期
病理因素
预后
复发
ovarian neoplasms
granular cell tumor
prognosis
clinicalstage
pathologicfactors
prognosis
recurrence
