摘要
本文主要研究细胞凋亡过程中c－fos、p53和c－myc等基因的表达。方法：经8－Br－cAMP诱导人食管癌Eca－109细胞调亡，应用原位来交技术对c－fos、p53和c－myc基因的表达进行检测。结果：经过诱导的试验组和不经诱导的对照组c－fos、p53和c－myc基因的表达差异有显著性（P＜0．001）。结论：提示这些基因在细胞凋亡的发生发展过程中起着重要的作用。
Expressions of c - for,c - myc and P53 gene in apoptosis are studied in this report.Methed:Human Eca-109 cells were induced to apoptosis with 8 - Br- cAMP and hybridization in situ was used to detect these genes' expression in apoptosis.Results:The results showed that the expression of c - fos,c - myc and p53 gene in induced experimental groups and in non - induced control groups had marked difference (P<0.001) .Conlussions:It is suggested that c- fos,c - myc and P53 genes Play an important part in the occurrence and development of apoptosis.
出处
《河南肿瘤学杂志》
1997年第6期429-431,共3页
Henan Journal of Oncology
