摘要
通过96h急性毒性实验敌百虫对鲫鱼的LC50为63.97mg/L,95%可信限为1.81±0.048 mg/L,95%可信区间为57.81~72.11 mg/L。分别选取1/2、1/4、1/8及1/16LC50为染毒浓度,于实验开始后24、48、72及96h采样分析,结果表明随着暴露时间的延长,各浓度组实验鱼血浆胆碱酯酶的活性均有一定的升高,但各浓度组间没有表现出明显的区别。实验剂量下的敌百虫对鲫鱼血浆GST活性有一定的影响,呈现出较为明显的先扬后抑的结果。1/2LC50实验组血浆CAT在实验进行至96h活性明显高于对照组,而其他剂量组在实验期间CAT活性没有明显的改变。本实验中敌百虫对鲫鱼的遗传性在微核率上未表现出差异,但高浓度核异常率在实验24。
Toxicity test of trichlorfon on crucian of 96 hour was did , the result showed that： LC50 is 63.97mg/L, 95% confidence limit is 63.97mg/L, 95% confidence interval is 57.81 -72. 11 mg/L. The exposure concentration is respectively is 1/2,1/4,1/8 and 1/ 16LC50, sample was analysis at 24,48,72and 96 hour after begin of test. The result showed that the activities of cholinesterase in plasma of crucian of test group all were higher than con- trol group; but difference among test group was not found. The trichlorfon influnced the activities of GST in liver of crucian,the activities were first risen and then decreased. The activities of CAT in liver of crucian of 1/2LC50 is higher than control group at 96 hour after test. The micronuclear rates of crucian almost did not changed, but the dyskaryosis of test group was higher than control group.
出处
《水产学杂志》
CAS
2008年第1期68-73,共6页
Chinese Journal of Fisheries
基金
国家科技基础条件平台项目(2004DEA70880)
关键词
鲫鱼
敌百虫
急性毒性
crucian
trichlorfon
acute toxicity
