摘要
于１９９２年在福建省对疾病监测点自然人群中１～９岁儿童乙型肝炎疫苗免疫后的效果进行研究，按照全国肝炎流调抽样方案，应用放射免疫（ＲＩＡ）试剂盒检测，共调查儿童７５８人，结果显示未免疫组和免疫组儿童的ＨＢｓＡｇ阳性率分别为２３．１６％和４．７９％，抗－ＨＢｓ阳转率由免疫后第１年的８９．２９％降低至免疫后第６年的６６．６７％。
A survey was carried out for immune effect among 1-9 years old children who had been immunized with Hepatitis B vaccine from normal population in the disease surveillance points in Fujian province. According to the unified programme of the national hepatitis seroepidemiological survey, 758 children were investigated. The samples were tested by RIA kit. The results showed as follows. Compared with the HBsAg positive rate (23.16%) among the nonvaccinated children, the HBsAg positive rate among the vaccinated children was declined to 4.79%, and the effectiveness was 79.23%. AntiHBs positive conversion rate (S/N≥2.1) was from 8929% at the 1st year to 66.67% at the 6th year of vaccination. The results indicate that the Hepatitis B vaccination possesses a good protective efficacy.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1997年第4期372-374,共3页
Chinese Journal of Experimental and Clinical Virology
