摘要
目的观察普鲁卡因程序输注及恒速滴注对平均动脉压（ＭＡＰ）和心率（ＨＲ）的影响。方法１２只杂种家犬随机分成两组，每组６只，体重相近。Ⅰ组１ｍｇ·ｋｇ－１·ｍｉｎ－１恒速滴入１％盐酸普鲁卡因；Ⅱ组程序输入盐酸普鲁卡因，滴注时间均为７０ｍｉｎ，观测ＭＡＰ、ＨＲ。结果普鲁卡因程序输注对家犬ＨＲ的影响与普鲁卡因恒速滴注对其影响相近，普鲁卡因程序输注对ＭＡＰ的影响与恒速滴注相比，只有１５ｍｉｎ点下降显著，余各点下降程度相近。结论普鲁卡因程序输注早期对ＭＡＰ影响显著。
Objective To observe the effects of program infusion and constant infusion of procaine hydrochloride on hemodynamics.Method Twelve mongral dogs were divided into two groups. In group Ⅰ(n=6) procaine HCl was infused at a constant rate of 1mg·kg -1 ·min -1 . In group Ⅱ(n=6) procaine HCl was adjusted by a microcomputer on the basis of calculated parameters with two compartmental linear model, as to attain the desired procaine level in a shorter time.Results Similar changse in HR and MAP were observed in both groups except that MAP in Group Ⅱ significantly decreased compared with that in group Ⅰ at 15 min after the start of infusion.Conclusion Program infusion of procaine affected MAP significantly during early infusion time.
出处
《徐州医学院学报》
CAS
1997年第3期234-237,共4页
Acta Academiae Medicinae Xuzhou
基金
江苏省教委自然科学基金
关键词
普鲁卡因
血流动力学
静脉麻醉
MAR
HR
Procaine Anesthesia, intravenously Infusion,computer-assisted Hemodynamics
