摘要
目的研究了超微粉碎贻贝壳粉(其中ф2μm占80%以上)作为钙补充剂的可行性。方法出生21d断乳SD大鼠50只,喂低钙饲料10d,随机分成5组,♀♂各半。用低钙饲料(对照组)、低钙饲料混合不同剂量市售L-乳酸钙以及混合不同剂量超微贻贝壳粉分别喂养4w,以大鼠的终身长、体重、钙吸收率、血清钙、血清磷以及骨骼、骨骼肌、心肌、血细胞、肝脏和肾脏中的钙含量及碱性磷酸酶活性为观察指标。结果超微贻贝壳粉作用效果与市售L-乳酸钙相仿。结论超微贻贝壳粉能被大鼠很好地吸收利用,可作为钙补充剂使用。
Objective To study the possibility of ultramicro-mussel shell powder （Φ2μm〉 80%） as a calcium supplement. Methods Weanling SD rats （21 days after birth, n=50） were fed with low calcium forage for 10 days, then were divided into 5 groups randomly with 10 rats in each group, half male and half female. Group I was control group fed on low calcium forage. Group Ⅱ～Ⅲ were fed on low calcium with L-lactic acid calcium . Group Ⅳ～Ⅴ were fed on low calcium forage with ultramicro-mussel shell powder. The experiment period was 4 weeks. The indices were including the eventual weight and length of the rats, the cal- cium absorption rate of calcium supplement, the concentrations of serum calcium, serum phosphorus, bone calcium, skeletal muscle calcium, myocardial calcium, hemocyte calcium, liver calcium, kidney calcium and the activity of alkaline phosphatase were assessed. Results The effect of ultramicro-mussel shell powder group was similar to L-lactic acid calcium. Conelusion The ultramicro-mussel shell powder can be well absorbed and utilized, and it can be used as a calcium supplement.
出处
《中国海洋药物》
CAS
CSCD
2008年第3期24-27,共4页
Chinese Journal of Marine Drugs
基金
浙江省教育厅项目资助(20050110)
关键词
厚壳贻贝壳
钙补充剂
钙吸收
Mytilus coruscus shell
calcium supplement
calcium absorption
