摘要
本文研究了磺酸型双子表面活性剂的中间体—3-氯-2-羟丙基磺酸钠合成工艺条件:反应体系的pH值为6～6.5,环氧氯丙烷、亚硫酸氢钠按1:1.6(mol/mol)比例在1.5h滴入,然后控制反应温度为20℃～30℃,搅拌反应4h。
3-Chloro-2-hydmxypmpyl sulfonate is one of the important medical intermediates, which forms anion Gemini suffactant . It was prepared by reacting epichlomhydrin with an excess tool sodium hydrogen sulfite. The proper technology paramenters for the process was obtained that the pH of the mixture was 6 - 6.5, the molar ratio of epichlomhydrin to sodium hydrogen sulfite was 1 ： 1.6,the temperature of reaction is 20℃- 30℃, and the time for the reaction was 4h.
出处
《齐齐哈尔大学学报（自然科学版）》
2008年第1期1-3,共3页
Journal of Qiqihar University(Natural Science Edition)
基金
黑龙江省教育厅科学技术研究项目(编号:10551334)
