摘要
研究了螺旋藻多糖 (PS)对环磷酰胺 (CY)引起的 BALB/C小鼠造血功能等损伤的保护作用。当给小鼠 CY时若能同时给予 (1 0 0 mg/kg) PS时 ,就能大大减轻因给予 CY引起的造血功能障碍 (P <0 .0 0 1 ) ;能明显减缓动物因使用CY所致的体重下降 (P <0 .0 2 )以及能明显减低因 CY作用的动物死亡率 (P <0 .0 5 )。提示使用 PS对预防或减轻化疗制剂的危害是具有明显作用的。为临床化疗、放疗病人使用 PS提供了依据。
We studied the protecting effect of Polysaccharide of Spirulina (PS) on hemopoietic malfunction of balb c mice caused by cyclophasphamid (CY). When mice were used CY and given PS(100 mg·kg -1 ) at the same time, it can decrease effectually that hemopoietic malfunction induced by CY (P<0.001). It can delay obviously its body weight decreased by CY (P<0.02) and can reduce death rate of them (P<0.05). From this study, we concluded that PS had a beneficial effect on chemotherapy and radiotherapy.
出处
《海洋科学》
CAS
CSCD
北大核心
1997年第6期36-39,共4页
Marine Sciences
