摘要
目的:应用MDCTA(多排螺旋CT血管成像)评价颈动脉斑块的特征以及不同性质斑块与缺血性脑卒中之间的关系。方法:回顾性分析3682例患者的头颈部CTA结果和临床资料。以斑块的密度、形态以及纤维帽的完整性,作为斑块风险性的评价指标。比较不同性质斑块之间临床症状的异同。结果:3682例接受头颈部CTA检查的患者中,有1984例检出动脉硬化斑块,其中1728例为双侧颈动脉发病。在1170例检出高风险斑块患者中,临床有反复TIA发作或脑梗死者728例;仅发现稳定斑块(不含高风险斑块)的814例中,临床有反复TIA发作或脑梗死者146例。经卡方检验,高风险斑块和稳定斑块之间临床表现有显著差异。结论:颈动脉粥样硬化斑块多为双侧发病。不稳定斑块是造成TIA发作或脑梗死的重要因素,应积极干预。
Objective：To explore the The relationship between the characteristics of carotid artery plaque and isehemic stroke in patients who had been performed MDCTA. Methods： 3 682 cases with bead and neck CTA results and clinical data were analyzed retrospectively. The density, shape and fiber apparatus integrity of the plaque were cosidered as the risk evaluation index of the plaque. To compare the differents of the clinical symptoms between patients with various plaques. Results： Atherosclerotic plaque were detected in 1 984 cases from 3 682 cases with head and neck CTA, including 1 728 cases of bilateral carotid artery disease. There were 728 cases who were diagnosed clinical TIA or repeated cerebral infarction in 1170 cases who had high -risk plaques. There were 146 cases who were diagnosed clinical TIA or repeated cerebral infarction in 814 patients who had stable plaques. The difference of clinical manifestations between high -risk plaque and stable plaque was noted（P 〈0. 01 ）. Conclusion： Carotid atherosclerostic plaque was often involved bilateral arteries. High -risk plaque was a very impostor factor to lead to cerebral infarction and CTA. We should pay close attention to the intervention of unstable plaques.
出处
《中国医药导刊》
2008年第3期334-335,共2页
Chinese Journal of Medicinal Guide
