摘要
目的通过对慢重肝(乙型)患者进行血浆置换治疗,观察其对慢重肝患者的影响,探寻降低不良影响的对策。方法治疗组276例慢重肝(乙型)患者,共进行827次血浆置换治疗,观察治疗前后血常规、肝功能、凝血指标、血氨、血气分析等指标的变化,治疗过程及治疗后患者的反应等,并针对不良影响给予不同的相应处理,观察不同处理的效果差异。结果可观察到过敏,胃肠道反应,心血管系统、中枢神经系统、神经肌肉系统、血液系统,以及创口渗血、电解质及酸碱平衡紊乱等不良反应,但同时,这些不良反应具有可预防性及通过支持治疗后的可恢复性。结论血浆置换应用于慢重肝的救治,对患者的多方面会有一定的影响,应做好相应的预防及术后支持治疗,避免或降低不良反应的发生。
OBJECTIVE Chronic severe hepatitis （B） patients were treated using plasma exchange to observe the results of treatment and explore the counterplans of decreasing adverse reactions. METHODS Treatment group had 276 cases chronic severe hepatitis patients who received 827 times plasma exchanges. Changes of indexes including blood routine, liver function, coagulation marker, blood ammonia ,blood gas analysis were detected before and after the treatment. Treatment course and reactions happening after the treatment were observed. Adverse reactions were dealt with different methods and the results were observed according to corresponding methods. RESULTS Adverse reactions such as allergic reaction, gastro-intestinal tract reaction, cardiovascular system reaction,center nervous system reaction, neuro-muscular system reaction, hematological system reaction, blood oozing, acid-base and electrolytic disturbance were observed, but these adverse reactions could be prevented and recovered through support therapy. CONCLUSION Plasma exchange had certain influence on treating chronic severe hepatitis from many aspects. Prevention and support therapy should be taken to avoid or decrease adverse reactions.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2008年第3期265-268,共4页
Chinese Journal of Modern Applied Pharmacy
关键词
血浆置换
不良反应
慢重肝
plasma exchange
adverse reaction
chronic severe hepatitis
