期刊文献+

厄贝沙坦对高血压患者全麻气管插管血流动力学的影响 被引量:1

下载PDF
导出
摘要 目的:评价口服血管紧张素受体拮抗剂-厄贝沙坦减轻高血压患者全麻气管插管的心血管反应的临床效果。方法:30例美国麻醉医师协会体验分级(ASA)Ⅰ-Ⅱ级拟在全麻下行胆囊切除术的择期手术患者,随机分为A组(厄贝沙坦组)、B组(对照组),每组15例,分别于服药前、诱导前、插管后即刻、插管后5min,记录上述收缩压(SBP)、舒张压(DBP)、心率(HR)、心率收缩压乘积(RPP)。结果:A组服药后,诱导前SBP下降,插管后3min,5minSBP血压无明显上升,两组SBP、DBP差异明显(P〈0.01)。A、B组麻醉诱导期HR均有所上升,但B组在诱导后3min、5min上升明显(P〈0.05),两组比较在插管后即刻有明显差异(P〈0.01)。RPP,A组在麻醉诱导前后无明显变化,B组在插管后即刻至插管后5minRPP明显升高,两组比较有明显差异(P〈0.05或P〈0.01)。结论:预防性口服厄贝沙坦可明显减轻高血压患者全麻气管插管的心血管反应。
出处 《中国中西医结合外科杂志》 CAS 2008年第3期220-222,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
基金 浙江嘉兴市科技局计划项目(2005AY3039)
  • 相关文献

参考文献5

二级参考文献37

  • 1杨军良,陈伯銮,赵树元,高仁果,高丽.不同麻醉方法对心率变异性的影响[J].中华麻醉学杂志,1995,15(1):5-9. 被引量:19
  • 2李明强.心率变异性分析在围术期的应用[J].国外医学(麻醉学与复苏分册),1996,17(5):298-301. 被引量:21
  • 3Guidelines subcommittee. 1999 World Health Organization-International Socity of Hypertension Guidelines for the management of hypertension. Journal of Hypertension, 1999,17.151.
  • 4Omote K,Kirita A,Namiki A,et al. Effects of nicardipine on the circulatry responses to tracheal intubation in normotensive and hypertensive patients. Anaesthesia, 1992,47.24.
  • 5Akselrod S,Grodon D,Ubel FA,et al. Power spectrum analysis of heart rate fluctuation: quantitative probe of beat-to-beat cardiovascular control. Science, 1981, 213:220.
  • 6Pagani M, Lombardi F, Guzzetti S, et al. Power spectral analysis of heart rate and arterial pressure variabilities as a market of sympathovagal interaction in man and conscious dog. Circ Res, 1986,59:178.
  • 7Lombardi F, Malliani A,Pagani M,et al. Heart rate variability and its sympathovagal, modulation. Circ Res, 1996,32:208.
  • 8Licker M,Schweizer A, Hohn L, et al. Cardiovascular responses to anesthetic induction in patients chronically treated with angiotensin-converting enzyme inhibitors,Can J Anaesth,2000,47:433.
  • 9Burnier M, Brunner H R. Angiotensin receptor antagonists[J].Lancet,2000, 355: 637-645.
  • 10Matsoukas J M, Bigam G, Zhou N, et al.^1H-NMR studies of [Sar^1] angiotensin Ⅰ conformation by nuclear Over- hause effect spectroscopy in the rotating frame (ROESY): Clustering of the aromatic rings in dimethylsulfoxide[J].Peptides,1990,11:359-366.

共引文献36

同被引文献8

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部