摘要
目的观察中药芪蛭消癥胶囊治疗糖尿病肾病(DN)的临床疗效。方法将DN患者112例随机分为2组,对照组56例予控制血糖、监测并控制血压等常规治疗;治疗组56例在对照组治疗基础上加用芪蛭消癥胶囊,每次4粒,每日3次。2组均连续治疗2个月为1个疗程,观察治疗前后24h尿蛋白定量(Upro)、血尿素氮(BUN)、肌酐(Cr)、尿β2微球蛋白(β2-MG)、糖化血红蛋白(HbAlc)、血脂及血液流变学变化。结果Upro、BUN、Cr、尿β2-MG2组治疗后比较差异均有统计学意义(P<0.01);HbAlc、血脂及血液流变学指标2组治疗后比较差异均有统计学意义(P<0.05);治疗组显效率、总有效率均高于对照组,2组比较差异均有统计学意义(P<0.05)。结论芪蛭消癥胶囊治疗DN疗效较好,在减少尿蛋白、改善肾功能、降低血脂等方面具有重要作用。
Objective To observe the effect of Qizhi Xiaozheng capsule on diabetic nephropathy. Methods 112 patients with diabetic nephropathy were randomly divided into two groups. Patients in control group （ n = 56） were treated by routine therapy. Patients in treatment group （ n = 56） were treated by combination of routine therapy and Qizhi Xiaozheng capsule （4 pills, three times a day ）. The therapeutic course was 2 months in both groups. 24 hr Urine protein （Upro）, blood urine nitrogen （BUN）, creatinine （Cr）, β2 - MG, HbMc, blood fat and hemorrheology were observed before and after treatment in both groups. Results There were significant difl＇erences on UPro, BUN, Cr, β2 - MG, HbAlc, blood fat and hemorrheology between two groups （ P 〈 0.01, P 〈 0.05）. Conclusion Qizhi Xiaozheng capsule can effective treat diabetic nephropathy, and play a role on improvement of Upro, renal function and blood fat.
出处
《河北中医》
2008年第6期570-572,共3页
Hebei Journal of Traditional Chinese Medicine
基金
河北省科学技术研究与发展指导计划(第一批)课题(编号:062476136)
关键词
糖尿病肾病
补气
补肾
祛瘀
Invigorate vital energy
Tonify the kidney
Remove ecchymosis
Diabetic nephropathy
