期刊文献+

趋化因子和肿瘤坏死因子与糖尿病肾病的相关性分析 被引量:2

下载PDF
导出
摘要 目的:观察2型糖尿病肾病(DN)患者血清RANTES、TNF-α的变化。方法:选择2型糖尿病患者60例,分为正常尿蛋白组(DM组)、微量白蛋白尿组(DN1组)、临床蛋白尿组(DN2组)。测定糖尿病患者和20例健康对照者血清RANTES、TNF-α。结果:血清RANTES、TNF-α水平DM各组均明显高于对照组(P<0.05);DN1组和DN2组均显著高于DM组(P<0.01);DN2组显著高于DN1组(P<0.01)。结论:DM患者血清RANTES、TNF-α水平明显升高,与DN病变程度平行。
出处 《中国误诊学杂志》 CAS 2008年第21期5109-5110,共2页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献3

  • 1Xu H,Nakayama K,Ogawa S,et al, Elevated plasma concentration of IP-10 in patients with type 2 diabetes mellitus[J]. Nippon Jinzo Gakkai Shi,2005,47(5) :524-530.
  • 2Herder C ,Pehonen M, Koeniq W. Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes :results from the [J ], Finish Diabetes Prevention Study Diabetes, 2006,55 (8) 2340-2346.
  • 3Navarro JF,Milena FJ ,Mora C,et al. Renal pro-inflammatory cytokine gene expression in diabetic nephropathy: effect of angiotensin-convertlng enzyme inhibition and pentoxifylline administration[J]. Am J Nephrol, 2006,26 (6) : 562-570.

同被引文献9

  • 1吴国仲,吴永贵.糖尿病肾病发病炎症机制研究进展[J].国外医学(泌尿系统分册),2005,25(3):363-367. 被引量:46
  • 2甄明富,谭晓军,邝树均.缬沙坦联合阿魏酸钠治疗早期糖尿病肾病的临床研究[J].实用全科医学,2006,4(6):650-651. 被引量:10
  • 3廖爱能,陈爱萍,钟鸿斌,金哲,王小华.氯沙坦对糖尿病肾病细胞间粘附分子-1的影响[J].实用全科医学,2007,5(2):124-125. 被引量:4
  • 4Xu H, Uysal KT, Becherer JD, et al. Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity [ J ]. Diabetes, 2002,51 : 1876- 1883.
  • 5Fernandez-Real JM, Lainez B, Vendrell J, et al. Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mel- litus[ J]. Am J Physiol Endocrinol Metab,2002,282 :E952-E959.
  • 6Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling[J]. Diabetes Care ,2004,27 : 1487-1495.
  • 7Paquot N, Castillo M J, Lefebvre PJ, et al. No increased insulin sensitiv- ity yafter a single intravenous administration of a recombinant human tumo rnecrosis facto rreceptor:Fc fusion protein in obese insulin-resistant patients [ J ]. Clin Endocrinol Metab ,2000,85 : 1316-1319.
  • 8Mishima Y, Kuyama A, Tada A, et al. Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with type 2 diabetes mellitus [ J ]. Diabetes Res Clin Pract, 2001,52 : 119- 123.
  • 9张从新,张秋林,罗宏斌.240例社区糖尿病肾病的进展状况分析[J].实用全科医学,2008,6(1):33-34. 被引量:13

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部