摘要
目的:观察帕米膦酸二钠合并化疗对骨转移引起疼痛的疗效,生活质量的改善和不良反应。方法:对54例临床确诊为骨转移癌的患者随即分成两组。对照组(26例,给予常规化疗)和治疗组(28例,在对照组的基础上加用帕米膦酸二钠)进行临床观察。结果:治疗组总有效率82.1%,对照组的总有效率57.7%,具有显著性差异(P<0.05);各主要系统的不良反应治疗组较对照组轻。结论:帕米膦酸二钠合并化疗对骨转移癌有良好的止痛效果且不良反应少。
Objective：observing pamidronate disodium and chemotherapy＇s curative effect on pain caused by osseous metastasis,its function on improvement of life quality and side reaction as well. Methods： deviding 54 sufferers who are diagnosed clinically as osseous metastasis into two groups ： matchedgroup（ 26 cases, giving common chemotherapy） ; treatment group（ 28 cases, adding pamidr-onate disodium based on common chemotherapy）and has clinical observation. Results： total effective percentage of treatment group is 82.1% while that of matched group is 57.7 %, the former＇s effectiveness is superior to the latter（P〈0.05） and has no undesirable side effects to the main systems. Conclusions： pamidronate disodium has favourable effects to kill pain caused by osseous metastasis and has light side effect.
出处
《中国民康医学》
2008年第13期1451-1451,1453,共2页
Medical Journal of Chinese People’s Health
关键词
骨转移
帕米膦酸二钠
帕米膦酸二钠合并化疗
止痛
Osseous metastasis
Pamidronate disodium
Pamidronate disodium and chemotherapy
Pain killing
