摘要
目的：观察水痘疫苗对水痘的保护效果。方法：选择广州市2002～2004年的水痘病例,按性别、年龄、户籍和居住地为每个病例选择1个对照,利用儿童免疫接种管理系统采集相关免疫信息。结果：共有856对病例及对照纳入研究,1剂水痘疫苗对水痘的保护效果为90.0%（95%CI86.3%～92.7%）,国产水痘疫苗的保护效果为93.5%（95%CI89.7%～95.9%）,进口水痘疫苗的保护效果为89.7%（95%CI72.9%～96.1%）。结论：上市后疫苗效果研究表明1剂水痘疫苗对低年龄儿童水痘有很好的保护效果。
Objective： To assess the effectiveness of varicella vaccine to prevent varicella. Methods： Cases were children who were suffering varicella in Guangzhou during the year 2002 to 2004. For each case, 1 control was selected, matched by gender, age, local or floating residence, residing in the same village or street. Immunization records were obtained from Children EPI Admlnistmtive Computer- ized System. Results： 856 pairs were enrolled. For one dose vaccine versus none, the vaccine effectiveness amounted to 90. 0% （95% CI 86. 3% -92.7% ） . For domestic-made varicella vaccine, the vaccine effectiveness amounted to 93. 5% （95%CI 89. 7% -95. 9% ） ; For foreign-made varicella vaccine, the vaccine effectiveness amounted to 89. 7% （95% CI 72. 9% -96. 1% ） . Conclusion： This post licensure study of varicella vaccine effectiveness finds that one dose vaccine versus none to be highly effective in preventing varicella in younger children.
出处
《中国妇幼保健》
CAS
北大核心
2008年第10期1353-1355,共3页
Maternal and Child Health Care of China
基金
2005YB194广州市卫生局立项广州市预防接种规范化门诊信息网络建设研究项目
关键词
水痘
保护效力
病例对照研究
Varicella
Vaccine effectiveness
Case - control study
