摘要
目的重点研究在不同温度下猪皮肤组织的拉压行为,探讨温度和真皮层胶原质热变性对皮肤组织力学性质的影响。方法实验采用新鲜猪皮,在特殊设计的温控制拉伸系统和压缩系统条件下观察猪皮肤在不同温度下的拉压行为。结果在拉伸实验中,皮肤的刚度随着温度的升高而降低,而在压缩实验中则相反。结论温度对皮肤组织的拉伸和压缩行为都有影响:拉伸性质的变化主要是由于随着温度的升高皮肤胶原蛋白的热变性所引起,而压缩性质的变化则有可能是由于在热变性的影响下水合的变化所引起。
Objective This paper aims to characterize the tensile and compressive behaviors of skin tissue under different temperatures and to study the effect of temperature and corresponding dermal collagen denaturation on the mechanical properties of skin tissue. Methods The uniaxial tensile and compressive tests of fresh pig ear skin under different temperatures have been performed by using two specifically-designed hydrothermal experimental systems. Resu]ts In tensile tests, the skin stiffness decreases with increased temperature, while a contrary trend is observed in compressive tests. Conclusion The results show that temperature has a great influence on both tensile and compressive properties of skin tissue, but the mechanisms are different. The variation of skin tensile properties is caused by the thermal denaturation of skin collagen with increased temperature, while the variation of skin compressive behavior of skin tissue may be due to the hydration change with thermal denaturation.
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2008年第3期247-251,共5页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
英国剑桥大学海外留学生奖学金计划、海外信任奖学金计划
西安交通大学校基金
国家外国专家局高等学校学科创新引智计划(No.B06024)
国家自然科学基金资助项目(No.10572111,10632060)
关键词
皮肤组织
热变性
热力学行为
拉伸行为
压缩行为
skin tissue
thermal denaturation
thermomechanical behavior
tensile behavior
compressive behavior
