摘要
目的：回顾性分析新型非黏附性液体栓塞材料Onyx栓塞脑动静脉畸形32例的效果。方法：32例脑动静脉畸形患者为2005—08／2007—08中国医科大学附属盛京医院收治，应用美国MTI公司生产的Onyx液态剂栓塞进行了36次血管内栓塞，栓塞供血动脉56支。栓塞后进行了6个月～2年的随访，了解病灶的闭塞情况，是否出现再出血、抽搐以及材料宿主反应。结果：32例脑动静脉畸形栓塞后，病巢全部栓塞为8例（25％），栓塞〉90％10例（31％），栓塞70％～90％9例（28％），栓塞50％～69％5例（16％）。完成随访31例，1例失访，栓塞后死亡1例，再出血2例，1例微导留置，栓塞后仍有癫痫发作2例。结论：Onyx血管内栓塞脑动静脉畸形是完全、永久地闭塞病灶，其治疗周期短、微创、安全、并发症少。
AIM： To conduct a retrospective analysis on the effect of Onyx, a new liquid embolic material, on treating arteriovenous malformations （AVMs）.
METHODS： Thirty-two brain AVMs patients were recruited from the Shengjing Hospital of China Medical University （Shenyang, Liaoning, China） from August 2005 to August 2007. They were treated by a total of 36 endovascular embolization in 56 feeder vessels with Onyx （MTI, USA）. The duration of follow-ups was 6-24 months. The focal occlusion, rehaemorrhagia, spasms and host response were all detected.
RESULTS： Among 32 AVMs patients undergoing endovascular embolization, 8 patients （25%） were cured by embolization only, 10 patients （31%） developed more than 90% embolization of the AVM nidus, 9 patients （28%） developed 70%-90% embolization, and 5 patients （16%） developed 50%-69% embolization. One case was lost and 31 cases completed the follow-ups. One case death occurred after embolization, hemorrhagic complication happened in 2 cases, epileptic attack happened in 2 cases and microcatheter withdraw failure in 1 case.
CONCLUSION： The favorable outcome and low complications in this study indicate that the embolization with Onyx is a safe, micro-invasive and effective method of the complete and permanent occlusion for endovascular treatment of the patients with brain AVMs.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第23期4528-4530,共3页
Journal of Clinical Rehabilitative Tissue Engineering Research
