摘要
目的:探讨肝移植术后免疫抑制状态下肿瘤发病率的变化及临床对策。方法:1例患者男性,51岁,先后因肝癌及肿瘤复发行2次肝移植术,术后给予联合免疫抑制治疗,再次肝移植术后出现急性排斥反应,给甲强龙冲击治疗。结果:再次肝移植术后一年继发喉神经内分泌癌,行喉癌根治术+放疗。结论:肝移植术后免疫抑制状态会提高某些肿瘤的发病率,有根治指征时,果断进行根治手术是能惠及病人的最佳策略。
Objective：To discuss the changing of tumor incidence rate under immunosuppress state after liver transplantation and clinical countermeasure. Methods ：The patient is male,51 years old, He accepted liver transplantation twice for liver cancer and recurrent of the tumor. Results： He suffered from secondary laryngeal neuroendocrine carcinoma after one year to liver retransplantation. Total laryngectomy and cervical target radiotherapy were performed, Conclusion：After liver transplantation the immunosuppressive state will increase certain tumor incidence. If there are radical indications,radical surgery will be the best strategy.
出处
《现代肿瘤医学》
CAS
2008年第7期1210-1211,共2页
Journal of Modern Oncology
关键词
肝移植
神经内分泌癌
免疫抑制状态
liver transplantation
neuroendocrine carcinoma
immunosuppressive state
