摘要
在合成标题化合物的基础上，测定了其晶体结构．由于苯环邻位取代基的差异，导致了两者在空间构象上的极大差异，从而引起它们生物活性的绝然不同．与磺酰脲类除草剂的晶体结构进行比较后发现，这两类除草剂的空间构象与生物活性间的关系是完全一致的，从而进一步说明了它们与ALS可能具有相同的结合位点．
The title compound was syntheslzed and analysed by X-ray diffraction. The difference of ortho-substituents resulted in the great difference in conformation and their herbicidal activity. Compared with the crystal structures of herbicidal sulfonurea, the same structure-activity relationship as that of sulfonurea can be found in sulfonamides, which indicatedthat this two kinds of herbicides might have the same binding site on ALS.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1997年第12期1982-1986,共5页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
磺酰胺
晶体结构
构效关系
除草剂
Sulfonylamide
X-ray diffraction
Crystal structure
Structure-activity relationship
