摘要
目的探讨陆地与海上不同环境条件对海水浸泡犬复合型颅脑火器伤的影响。方法成年健康犬30只，制作成复合型颅脑火器伤动物模型（颅脑火器伤＋开放性胸部伤＋开放性腹部伤＋烧伤）。动物致伤后随机分为3组。即A组（陆地非海水浸泡）、B组（陆地海水浸泡）和c组（海上海水浸泡），每组10只。采用Powlab/8sp生理记录仪动态监测体温、呼吸（R）、心率（HR）和平均动脉压（MAP）的变化，监测血气分析和血电解质变化。结果C组伤情明显重于A组和B组，表现为生命体征紊乱，呼吸明显加快，循环、体温调节功能障碍，低体温，血浆渗透压引。高，高钠、高氯血症，代谢性酸中毒，导致动物生存时间缩短，死亡率增加。结论海上环境对海水浸泡复合型颅脑火器伤犬的生命体征和生化指标均有明显影响。
Objective To investigate effects of different environment of land and sea on combined injury with craniocerebral firearm wound （CICFW） in dogs immersed by seawater. Methods The model of CICFW including craniocerebral firearm injury,open chest injury, open abdominal injury and burn. The dogs with CICFW were randomly divided into three groups, each of which had 10 dogs： the group Ⅰ （ without seawater inlnlersion in land environment） , the grnup Ⅱ （with seawater immersion in land environment） , and the group Ⅱ （with seawater immersion on sea environment）. The changes of vital signs including body temperature, respiration, heart rates and mean arterial pressure were recorded by powlab/8sp electrophysinlograph. The blood gas analysis and electrolytes changes were monitored. Results The state of an injury was severer in group Ⅲ than that in group Ⅰ and group Ⅱ. Compared with group I and group Ⅱ , the respiration and heart rates in group Ⅲ were significantly faster （P〈0.05）. In addition, recireulating system and body heat regulation function were failure in group Ⅲ, as well as low temperature, high plasma osmotic pressure, hypsi-sodium, hyperchloraemia and metabolic acidosis were also vital sigu of group Ⅲ, which of all above them made live time of animals shorten and mortality rate increase. Conclusions The sea environment is one of important influence factors that cause the changes of vital signs and biochemical indicator after CICFW.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2008年第3期135-138,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
基金
基金项目：全军医学科学技术研究“十一五”计划课题（06MBl74）
关键词
复合伤
颅脑火器伤
开放性胸部伤
开放性腹部伤
烧伤
海水浸泡
动物模型
Combined injury
Cranioeerebral firearm wound
Open chest injury
Open abdominal injury
Burn
Seawater immersion
Animal model
