摘要
性腺是对电离辐射高度敏感的器官之一,但电离辐射造成性腺丧失生殖能力是有阈剂量的。^(131)Ⅰ治疗甲状腺功能亢进症(甲亢)时,患者性腺的吸收剂量一般都小于这个阈剂量。现已证明,^(131)Ⅰ治疗育龄妇女或青少年和儿童甲亢,没有降低患者的生育能力,也未增加遗传损害发生率。对抗甲状腺药物无效、拒绝手术或有手术禁忌证的青少年和儿童甲亢,用^(131)Ⅰ治疗是可供选择的一种较好的治疗方法。
Gonadal gland is one of the highly sensitive organs to ionizing radiation, but there is a threshold dose for gonadal sterility caused by ionizing radiation. When ^131Ⅰ is applied in the treatment of patients with hyperthyroidism, the usually absorbed radiation dose of gonadal gland is below the threshold. It is documented that ^131Ⅰ therapy for fertile women or adolescents and children with hyperthyroidism does not cause reduction in fertility and does not increase the incidence of genetic defects. Therefore ^131Ⅰ therapy, for adolescents and children with hyperthyroidsm, who have been failed in anti-thyroid drug therapy, refused surgical treatment or were contraindicated in surgery, is another better available therapeutical modality.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2007年第6期481-483,共3页
Chinese Journal of Endocrinology and Metabolism
