摘要
目的研究脑桥梗死的危险因素、临床特点及预后情况。方法收集北京天坛医院神经内科收治入院的106例脑桥梗死患者的一般资料。评估患者的危险因素,分析临床症状及体征、病变部位及血管损害的特点;随访病后30d、90d的预后情况,分析与预后相关的因素。结果危险因素:脂代谢异常86例,高血压83例,有梗死前短暂性脑缺血发作(TIA)史者63例,吸烟59例,既往卒中史54例,糖尿病47例,饮酒45例,冠心病34例,高同型半胱氨酸血症27例。主要病因为动脉粥样硬化。临床表现:眩晕86例,构音障碍67例,感觉障碍51例,眼球运动障碍35例,偏瘫32例,眼震31例,复视30例,共济失调24例,四肢瘫23例,意识障碍18例,交叉瘫10例。年龄与预后不良呈正相关(OR=1.37,P<0.05)。此外,脑桥与近、远段同时受累(OR=6.69,P<0.01),基底动脉急性闭塞(OR=6.23,P<0.01)的患者预后不良。结论动脉粥样硬化是脑桥梗死患者的最常见病因。眩晕、构音障碍、感觉运动障碍是常见的临床表现。不同责任病变部位及病变血管的脑桥梗死患者预后不同。
Objective To study etiopathogenisis, risk factors, clinical manifestations and prognoses of pontine infarction. Methods General information of 106 pontine infarction patients, who were admitted in Neurology Department of Beijing Tiantan Hospital from 2004 - 1 to 2005 - 2, were collected and evaluated by NIHSS on admission. Their risk factors were assessed and clinical symptoms and characteristics of signs, lesions and vascular damage were analyzed. The patients were followed up to assess prognosis on days 30 and 90 after admission, and factors correlated with prognoses were probed into. Results Atherosclerosis was found to be the leading cause pf pontine infarction, accounting for 84. 6% of 106 patients. The causes behind it were smoking, hypertension, hypedipemia, diabetes mellitus. The clinical manifestations were vertigo （86 cases）, conscious disturbance （18 cases）, dysarthria （67 cases）, sensory disability （51 cases）, ocular motor disorder （35 cases）, hemiplegia （32 cases）, nystagmus （31 cases）, quadriplegia （23 cases）, diplopia （30 cases）. Ages wereposltively correlated with poor prognoses （ OR = 1.37, P 〈 0. 05 ） o In addition, patients with simultaneous involvement of pons and near - and far - paragraph （ OR = 6.69, P 〈 0. 01 ） and with acute basilar artery occlusion （ OR = 6. 23, P 〈 0.01 ） were more likely to have poor prognoses. Conclusion Atherosclerosis is the leading cause for pontine infarction. Its common clinical manifestations are vertigo, dysarthria, sensory disability, and hemiparalysis. Pontine infarction patients with different diseased regions and different vascular lesions have different prognoses.
出处
《中国全科医学》
CAS
CSCD
2008年第14期1252-1253,1256,共3页
Chinese General Practice
关键词
脑梗死
脑桥
预后
Cerebral infarction
Pons
Prognosis
