摘要
目的:了解燃煤型氟骨症患者血清Ca、P和ALP的变化。方法:分别测定99例燃煤型氟骨症患者和61例非病区健康人群血清Ca、P和ALP水平。结果:氟骨症患者血清Ca(2.12±0.24mmol/L)明显低于健康对照组(2.51±0.14mmol/L),血清P(1.24±0.41mmol/L)和ALP(90.22±29.21U/L)明显高于对照组(分别为1.09±0.28mmol/L和73.64±23.93U/L),差异均具有统计学意义(P<0.01)。结论:在排除其他代谢性骨病的条件下,血清Ca、P和ALP可作为氟骨症辅助诊断的生化指标。
Objective: To investigate the changes in levels of serum calcium, phosphorus and alkaline phosphatase in the patients with coal burning skeletal fluorosis. Methods: The biochemical indices,such as calcium, phosphorus and alkaline phosphatase in 99 cases with coal burning skeletal fluorosis and 61 cases in normal control group in non-endemic area were determined. Results: The value of serum calcium (2.12 ±0.24mmol/L) in skeletal fluorosis group was lower than that of normal control group(2.51±0.14mmol/L)(P 〈0.01), and those of serum phosphorus( 1.24 ± 0.41mmol/L) and alkaline phosphatase ( 90.22 ± 29.21U/L) were higher than that in normal control group(1.09±0.28mmol/L and 73.64±23.93U/L,respectively ) (P〈0.01). Conclusions: Serum calcium,phosphorus and alkaline phosphatase could play important roles in auxilia- ry diagnosis of skeletal fluorosis,except other metabolic bone diseases.
出处
《河北北方学院学报(医学版)》
2008年第4期27-28,共2页
Journal of Hebei North University:Medical Edition
基金
黔南民族医学高等专科学校科研项目(编号:QNYZ200703)
关键词
钙
磷
碱性磷酸酶
氟骨症
Calcium, Phosphorus, Alkaline Phosphatase, OSTEOFLUOROSIS