摘要
目的评价益脑胶囊治疗神经衰弱(肝肾不足、气阴两虚证)的临床疗效及其安全性。方法采用多中心、随机、单盲、平行对照临床研究方法(试验组益脑胶囊,对照组脑灵素胶囊),试验组342例,对照组111例。结果益脑胶囊治疗组临床愈显率为52.1%,总有效率为93.6%;对照组临床愈显率为36.0%,总有效率为82.8%。经统计学分析,治疗组疗效优于对照组,有显著性差异(P<0.01)。结论益脑胶囊治疗神经衰弱(肝肾不足、气阴两虚证)有良好的临床疗效,能明显改善患者的失眠等临床症状,且临床应用安全。
Objective To evaluate the clinical effect and safety of Yinao Capsules for neurasthenia with the syndrome of liver- kidney deficiency and Qi- yin deficiency. Methods A multi- center, randomized, single- blind and positive drug parallel controlled trial was adopted. Three hundred and forty -two cases in the treatment group were treated with Yinao Capsules, and 111 cases in the control group were treated with Naolinsu Capsules. Results Yinao Capsules had a total effective rate of 93. 6 % and the markedly effective rate of 52. 1%. Compared with Naolinsu Capsules, Yinao Capsules showed a better clinical effect （ P 〈 0.01 ）. Conclusion Yinao Capsules has certain therapeutic effect for neurasthenia with the syndrome of liver - didney deficiency and Qi - yin deficiency.
出处
《中药新药与临床药理》
CAS
CSCD
2008年第4期314-316,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
益脑胶囊
神经衰弱
肝肾不足
气阴两虚
Yinao Capsules
Neurasthenia
Liver - kidney deficiency
cy. - yin deficitncy
