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晶状体前囊膜在青光眼白内障联合手术的应用研究 被引量:8

Clinical study on the application of anterior lens capsule in trabeculectomy combined with cataract surgery
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摘要 目的:评价晶状体前囊膜在青光眼白内障联合手术中的临床效果及降压作用。方法:采用随机对照的方法,将30例(30眼)闭角型青光眼合并白内障患者分为实验组和对照组各15眼,实验组行小梁切除联合小切口白内障囊外摘除+人工晶状体植入术,术中将自体前囊膜衬垫在巩膜瓣下,对照组行小梁切除联合小切口白内障囊外摘除+人工晶状体植入术,术中一次性应用MMC,浓度0.33g/L,根据结膜、筋膜的肥厚程度不同,时间1~4min不等,随访6~12mo。主要观察指标:视力、眼压、滤过泡、手术成功率、角膜内皮细胞密度、术后并发症等。结果:实验组与对照组在功能性滤过泡的累积存活率,手术成功率、术后视力改善、角膜内皮计数密度、术后并发症无显著性差异;两组形成的滤过泡类型有显著性差异。结论:晶状体前囊膜应用于青光眼白内障联合术中可有效降低眼压,长期有效保留功能性滤泡,保持滤过道开放,且并发症较少。 AIM: To evaluate the clinical results of anterior lens capsule implantation in trabeculectomy combined with cataract surgery. METHODS. A total of 30 cases (30 eyes) with primary angle-closure glaucoma and cataract were randomly divided into 2 groups. Anterior lens capsule implantation in trabeculectomy with small-incision cataract surgery was performed on 15 eyes (experimental group) and mitomycin C (0. 33g/L) application in trabeculectomy with small-incision cataract surgery on other 15 eyes (control group). The local contact time was from 1 to 4 minutes according to pachynsis of bulbar conjunctiva and fascia, The follow-up time was ranged from 6 to 12 months. The effects of visual acuity, intraocular pressure, filtration bubble, corneal endothelial cells density, achievement ratio of operation and complications were analyzed. RESULTS: There was no significant difference on the rate of functional bleb formation, achievement ratio of operation visual acuity, intraocular pressure, corneal endothelial cells density and complications between experimental and control group. There was significant difference on kinds of bleb formation between these two groups. CONCLUSION: Anterior lens capsule implantation in trabeculectomy with cataract surgery can control intraocular pressure effectively, long-term sustain functional filtration bubble satisfactorily. Compared to the control group, anterior lens capsule implantation presents less complications.
出处 《国际眼科杂志》 CAS 2008年第7期1365-1367,共3页 International Eye Science
基金 中国江西省卫生厅资助项目 江西省卫生厅科技计划立项项目(No.041059)~~
关键词 晶状体前囊膜 青光眼 白内障 丝裂霉素 anterior lens capsule glaucoma cataract mitomycin C
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