摘要
目的制定消糖灵胶囊中盐酸小檗碱的含量控制标准。方法采用高效液相色谱法对方中的盐酸小檗碱进行含量测定,采用Discovery C184.6 mm×150 mm色谱柱,流动相为乙腈-0.025 mol/L磷酸溶液（25∶75）,检测波长350 nm。结果盐酸小檗碱进样量在0.00533-0.2132μg（r=0.9999）范围内呈良好的线性关系。平均回收率为98.5%（n=9）,RSD为1.6%。结论该方法简便,准确。
Objective To establish an HPLC method for determination of Berberine Hydrochloride in Xiaotangling Capsules. Methods With discovery column Cls ,the mobile phase was aeetonirile-0. 025 mol/L phosphoric acid （25：75 ）. The detection wavelength was 350 nm. Results The ieariin sample showed a good relationship in the range of 0. 005 33 -0. 213 2 μg, r = 0.999 9. The average recovery of adding sample was 98.5% （ n = 9 ） ,RSD was 1.6%. Conclusion The method is simple and accurate.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2008年第5期1106-1107,共2页
Lishizhen Medicine and Materia Medica Research
关键词
高效液相色谱
消糖灵胶囊
HPLC
Xiao tangling Capsules
Berberine Hydroehloride
