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乳腺癌组织pS2与雌激素和孕激素受体的关系及预后意义 被引量:2

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摘要 目的:探讨乳腺癌组织中ER与PR、pS2表达的临床意义及对预后的判断意义。方法:采用免疫组化S-P法检测53例术前未接受过化疗的原发性乳腺癌中ER与PR、pS2、的表达,采用χ2检验进行统计学处理。结果:pS2、ER、PR的表达与组织学分级呈负相关,随乳腺癌分级级别升高而降低;随乳腺癌病人术后生存期的延长而升高;pS2的表达与ER相关。结论:ER、PR、pS2联合运用可作为乳腺癌预后诊断的可靠指标。
作者 罗仁峰
机构地区 江汉大学医学院
出处 《亚太传统医药》 2008年第7期11-12,共2页 Asia-Pacific Traditional Medicine
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  • 1刘复生,李晓.乳腺癌的组织学分级与预后[J].中华病理学杂志,1993,22(1):36-37. 被引量:28
  • 2Kurosumi M.Significance of immunohistochemical assessment of steroid hormone receptor status for breast cancer patients.Breast Cancer,2003,10(2):97-104.
  • 3Bloom HJ,Richardson WW.Histological grading and prognosis in breast cancer;a study of 1409 cases of which 359 have been followed for 15 years.Br J Cancer,1957,11(3):359-77.
  • 4Matsuo K,Fukutomi T,Hasegawa T,et al.Histological and immunohistochemical analysis of apocrine breast carcinoma.Breast Cancer,2002,9(1):43-9.
  • 5Thike AA,Chng MJ,Fook-Chong S,et al.Immunohistochemical expression of hormone receptors in invasive breast carcinoma:correlation of results of H-score with pathological parameters[J].Pathology,2001,33(1):21-5.
  • 6王锡山,刘淑珍,王艳颖,杨为戈,薛英威,董新舒,赵家宏,李红丽.乳癌雌激素受体与孕激素受体测定的临床生物学意义[J].实用肿瘤学杂志,1997,11(2):105-106. 被引量:3
  • 7信涛,赵玉兰,冯占军,马国军,王建秋,郑伟.1336例乳腺癌组织中ER、PR的表达及临床意义[J].实用肿瘤学杂志,2001,15(2):100-102. 被引量:9

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  • 1刘铁成,鲁智,陶仪声,佘明金,王勤.乳腺癌pS2、PSA表达与ER、PR的关系及预后意义[J].蚌埠医学院学报,2004,29(6):487-488. 被引量:6
  • 2龚益平,吴昌鸣,杨小玲.乳腺癌ps2蛋白表达与临床病理关系的研究[J].肿瘤防治研究,2005,32(1):13-14. 被引量:5
  • 3陆辉,王水,夏添松.240例乳腺癌组织中p53、C-erbB-2表达的临床分析[J].江苏医药,2007,33(8):790-791. 被引量:10
  • 4MasiL,Recenti R,Silvestri S,et al Expression of Cyclooxygenase-2 in Osteosarcoma of Bone Applied Immunohistochemistry &MolecularMorphology,2007,15 ( 1 ) :70-76.
  • 5Lanza-Jacoby S, Burd R, Rosato FE Jr, et al Effect of simultaneous inhibition of epidermal growth factor receptor and cyclooxygenase-2 in HER-2/neu-positive breast cancer Clin Cancer Res, 2006, 15 (12) :6161-6169.
  • 6Grudzinski M, Cambruzzi E, Lahude E, et al COX-2and CD105 expression in breast cancer and disease-free survival Rev Assoc Med Bras ,2006,52 (4) .275-280.
  • 7Liu C H, Chang S H, Narko K, et al. Overexpressinon of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem,2001,276 : 18563-18569.
  • 8Ristimaki A, Sivula A, Lundin J, et al. Prognostic ssignificance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res, 2002,62 ( 3 ) : 632 -635.
  • 9Schwatz L H, Koemer FC, Edgerton SM, et al. PS2 expression and response to hormonal therapy in patients with advanced breast cancer. Cancer Res,1991,51 (2)624.
  • 10Thompson AM, Ehon RA, Hawkins RA, et al. IX52 mRNAexpression adds prognostic information to node status for 6-year survival in breast cancer. Br J Cancer,1998,77(3) :492.

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