摘要
目的：观察脑电图（ＥＥＧ）和脑地形图（ＢＥＡＭ）的脑电活动变化，以探索刺五加注射液对缺血性脑血管病的治疗作用。方法：利用ＥＥＧ和ＢＥＡＭ研究刺五加注射液治疗２６例缺血性脑血管病患者治疗前后的脑电活动变化，同时以１７例正常人ＥＥＧ和ＢＥＡＭ作对照。结果：缺血性脑血管病患者ＥＥＧ主要表现为指数明显减少〔（８．２５±０．７５）Ｈｚ对（１０．５０±２．５０）Ｈｚ，Ｐ＜０．０１〕，波幅明显降低，调节、调幅差；ＢＥＡＭ的主要表现为其能量分布的不对称性明显增高（２１．５８μＶ２对±３．５０μＶ２，Ｐ＜０．０１）。治疗后指数上升，波幅明显上升〔（３０±１０）μＶ对（８５±１５）μＶ，Ｐ＜０．０１〕；同时ＢＥＡＭ脑电能量分布的不对称性得到明显改善，左、右侧的平均差值明显降低（２１．５８μＶ２对±３．１１μＶ２，Ｐ＜０．０１）。结论：刺五加注射液具有改善缺血性脑血管病患者脑功能损害的作用。
Objective:To observe the changes in activity of electroencephalogram (EEG) and brain electrical activity map (BEAM) and to explore the therapeutic effect of acanthopanax senticosus injection on ischemic cerebral angiopathy (ICA).Methods:To study the changes in electroencephaloactivity of 26 cases of ICA before and after treatment with acanthopanax senticosus injection by EEG and BEAM,and compare to 17 normal subjects (control group).Results:The chief manifestation on EEG of ICA:the exponent was decreased significantly (8 25±0 75)Hz vs. (10 50±2 50)Hz, P <0 01 ,the scope of wave was dropped obviously,adjustment and amplitude modulation were difficult.On the BEAM of ICA,the asymmetry of energy distribution was increased significantly (21 58 μV 2 vs. ±3 50 μV 2, P <0 01).After treatment,the exponent was increased and wave scope was raised obviously (30±10)μV vs. (85±15)μV, P <0 01 .Moreover,the asymmetry of energy distribution was improved significantly,the difference of average value between the left and right side was decreased significantly (21 58 μV 2 vs. ±3 11 μV 2, P <0 01).Conclusions:Acanthopanax senticosus injection can improve the brain function of patients with ICA.
关键词
脑缺血
刺五加注射液
脑电图
脑地形图
中药品
ischemic cerebral angiopathy\ \ acanthopanax senticosus injection\ \ electroencephalogram\ \ brain electrical activity map
