摘要
目的观察静脉滴注丙种球蛋白治疗川崎病的治疗效果,并进一步探讨其有效治疗方案。方法将119例川崎病患儿随机分为三组,分别用三种不同的治疗方案:①对照疗法组:单用阿司匹林;②常规疗法组:静滴丙种球蛋白0.4g(/kg·d)×5d加阿司匹林;③冲击疗法组:静滴丙种球蛋白2g(/kg·d)×1d加阿司匹林。对比三种治疗方案对急性期症状的控制及防止冠脉病变的发生作为临床判断指标。结果常规疗法、冲击疗法治疗川崎病控制急性期症状及防止冠脉病变明显优于对照疗法,而冲击疗法控制急性期症状优于常规疗法,在防止冠脉病变方面,两者无显著性差异。结论在治疗川崎病三种方案中,常规疗法,冲击疗法均优于对照疗法,并以冲击疗法疗效最为明显,为最佳。
Objective To observe the effect of infusing r-globlin in treating Kawasaki disease and to further explore its effective regimen. Methods 119 children with Kawasaki disease were randomedly divided into three groups: (1)the control group: the patients were treated with aspirin only. (2)the routine method group: the patients were treated with r-globulin[0.4g/(kg·d)×5]plus aspirin. (3)the sharp method group- the patients were treated with r-golbulin[2.0g/(kg·d)× 1]plus aspirin. Results The routine method and the sharp method were more effective than the control method in controlling acute symptoms and preventing from the coronary disease,morever, the sharp method was better than the routine method in controlling acute symptoms rather than preventing from the conary disease. Conclusion The sharp method was the most attractive regimen of therapy for Kawasaki disease among all three methods,although the routine method was also more effective than the control method.
出处
《中国现代医生》
2008年第22期90-91,共2页
China Modern Doctor