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小脑顶核电刺激对脑卒中后抑郁及日常生活能力的影响 被引量:2

The Effect of Fastigial Nucleus Electric Stimulation on Depression and ADL of Patients with Stroke
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摘要 目的:观察小脑顶核电刺激治疗对脑卒中后抑郁患者的抑郁症状及日常生活能力的影响。方法:脑卒中后运动功能障碍伴抑郁患者60例,随机分成治疗组和对照组各30例,均接受康复运动及百忧解治疗,治疗组在此基础上加用小脑顶核电刺激,治疗5个疗程,治疗前和治疗后8周应用汉密顿抑郁量表评定抑郁症状,Barthel指数评定日常生活活动能力。结果:60例患者均完成治疗,治疗组治疗后汉密顿抑郁量表评分明显改善,显著低于治疗前和对照组(P<0.01);治疗组治疗后Barthel指数较治疗前提高,也高于对照组(P<0.05)。结论:小脑顶核电刺激可以减轻脑卒中抑郁症状,对患者情绪、日常生活能力的恢复有促进作用,效果优于单纯药物治疗。 Objective:To investigate the effect of fastigial nucleus electric stimulation on depression and ADL of patients with stroke. Methods: Sixty stroke patients with despression and motor dysfunction were divided into groups treatment and control, and treated with rehabilitation exercise and Fluoxetine. The treatment group was given fastigial nucleus electric stimulation with 5 courses. All the patients were evaluated with Hamilton depression rating scale and modified Barthel index before and 8 weeks after treatments. Results: After treatments, the scores of Hamilton depression rating scale of treatment group were lower than that before treatments and that of the control group(P〈0.01). The scores of ADL were better than that before treatments and that of the control group after treatments(P〈0.05). Conclusion: Fastigial nucleus electric stimulation can relieve despression after stroke, promote mood and ADL of the patients. The effect was better than medicine therapy only.
出处 《神经损伤与功能重建》 2008年第4期248-250,共3页 Neural Injury and Functional Reconstruction
关键词 脑卒中 抑郁 小脑顶核电刺激 日常生活能力 stroke depression fastigial nucleus electric stimulation activities of daily living
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