摘要
目的:探讨静脉注射丙种球蛋白冲击治疗新生儿ABO溶血病的疗效。方法:治疗组30例ABO溶血病患儿行静脉丙种球蛋白1g/(kg.d)单剂静脉冲击治疗;对照组31例给予静脉丙种球蛋白0.4g/(kg.d)静脉滴注,连用3d,对比分析两组临床疗效。结果:治疗组显效率(83.3%)及总有效率(100%)均明显优于对照组的19.4%、71.0%(χ2=24.949,P<0.05,χ2=26.962,P<0.05)。结论:静脉丙种球蛋白冲击治疗新生儿ABO溶血病可有效阻止溶血,降低胆红素浓度,减少胆红素脑病发生,值得临床推广使用。
Objective： To investigate the clinical effect of the stosstherapy of IVIG on ABO hemolytic disease of the newborn. Methods： To contrast the stosstherapy with a dosage of intravenous drip with 1 g/（ kg · d） of IVIG for 30 cases （the treatment group） and the conventional therapy with a dosage of intravenous drip with 0.4 g/（ kg · d） of IVIG for 31 cases （ the control group）, and analyze the curative effect. Results： The marked effective rate is 83.3% and the total curative rate is 100% of the treatment group were higher than those of the control group （ 19.0% and 71.0% ）. （χ^2 = 24. 949, P 〈 0. 05, χ^2 = 26. 962, P 〈 0.05 ）. Conclusions： Comparing the stosstberapy of IVIG with the regular therapy of IVIG for ABO-hemolytic disease of the newbem, the former could prevent hemolysis and reduce the occurrence of hilirubin encephalopathy as the level of hilirubin in serum decreased. It＇ s a valuable way to be spread clinically.
出处
《儿科药学杂志》
CAS
2008年第4期51-52,共2页
Journal of Pediatric Pharmacy
