摘要
目的:探讨老年尿毒症患者血液透析中低血压发生的相关因素,并观察钠模式和超滤模式联合应用对透析中低血压的作用。方法:收集46例维持性血液透析老年患者的临床资料,按有无透析中低血压分为低血压组(20例)和对照组(26例),两组进行相关因素的比较,并观察标准透析和联合应用钠模式和超滤模式在血液透析中低血压的发生情况。结果:低血压组透析中超滤量增加(P<0.05),血钠、血浆白蛋白降低(P<0.05),血尿素氮和肌酐两组间差异无显著性(P>0.05)。超声心动图的分析结果显示低血压组左室肥厚、左室收缩和舒张功能减退的程度均较对照组明显(P<0.05)。与标准透析相比,联合应用钠模式和超滤模式发生低血压的例数明显减少(P<0.01)。结论:老年尿毒症患者透析中低血压是由多种因素造成的,联合应用钠模式和超滤模式可减少透析中低血压的发生。
Objective To explore the factors related to hemodialytic hypotension in elderly uremic patients and observe the efficacy of combination of sodium profiling （SP） and ultrafiltration profiling （UP） in reducing intradialytic hypotension. Methods The clinical data of 46 patients with maintaining hemodialysis were collected. The patients were divided into hypotesion group （n=20） and control group （n=26） according to whether or not hemodialytic hypotension was present. The factors related to intradialytic hypotension were compared between the two groups and the efficacy of combination of SP and UP in reducing intradialytic hypotension was observed. Results The uhrafihration volume was higher, while serum natrium （Na） and albumin in hypotension group were lower than those in control group （P 〈 0.05）, blood urea nitrogen and serum creatinine were not significantly different between the two groups（P〉 0.05）. The analysis of echocardiology showed that left ventricular hypertrophy, systolic and diaslotic dysfunction in hypotension group were higher than those in control group （P 〈 0.05）. Compared with standard dialysis （SD）, the frequency of hypotension was obviously reduced in the combination of SP and UP（P 〈 0.01 ）. Conclusions Intradialytic hypotension is caused by many factors in elderly uremic patients undergoing hemodialysis. Hypotensive episodes significantly decreased in the combination of SP and UP.
出处
《实用医学杂志》
CAS
2008年第14期2404-2406,共3页
The Journal of Practical Medicine
关键词
尿毒症
低血压
肾透析
老年
钠模式
超滤模式
Uremia Hypotension Renal dialysis Elderly Sodium profiling Uhrafihration profiling
