摘要
目的：回顾性分析连续性肾脏替代治疗（ＣＲＲＴ）技术在重症急性肾功能衰竭（ＡＲＦ）救治中的应用及对预后的影响。方法：１９８６年５月～１９９７年６月用ＣＲＲＴ治疗重症急性肾功能衰竭患者６３例，并对ＣＲＲＴ装置、置换液配制和控制输入以及血滤器的重复使用等方面作了一系列改进。结果：６３例患者存活３５例，存活率５５．６％，分析了存活及死亡两组患者人口统计学资料、ＡＲＦ的特点、疾病严重程度（ＡＰＡＣＨＥⅡ）等因素。结论：①ＣＲＲＴ技术的改进促进了其临床应用；②重症ＡＲＦ的预后受患者年龄、既往健康状况、病情严重程度、ＡＲＦ特点等多种因素影响；③ＣＲＲＴ可以改善肾性ＡＲＦ患者的预后。
OBJECTIVE To evaluate the effects of continuous renal replacement therapy(CRRT) in the treatment of acute renal failure.METHODOLOGY This study included 63 severely illed patients complicated with acute renal failure who were hospitalized between 1986 and 1997. Their clinical data were reviewed retrospectively. The Acute Physiology and Chronic Health Evaluation(APACHE) II score were calculated before CRRT.RESULTS 35(556%) patients survived after the acute phase of their illness, while 28(444%) patients died. In the survived group, there were significantly less patients with parachymal renal diseases, refractory course of uremia, low APACHE II score before treatment, complication of ARDS, and the need of mechanical ventilation or vasoactive supporting treatment. No difference was found in the percentage of oliguria between the survived and died groups. CONCLUSION CRRT is a first choice in the treatment of ARF, especially in those complicated patients with severe parachymal renal diseases and multiple organ deficiency syndrome.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
1997年第5期415-421,共7页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
急性
肾功能衰竭
急救
肾脏替代疗法
连续性
continuous renal replacement therapy acute renal failure mortality
