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肾性骨营养不良检测进展

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摘要 肾性骨营养不良(ROD)主要包括高周转型骨病、骨软化症、无力型骨病、混合性骨病四种不同类型。高周转型骨病的骨形成率(BFR)明显升高,全段甲状旁腺激素(PTH)水平高。骨软化症,一般有低磷血症倾向,类骨质沉积大致正常,但不能正常钙化,易发生骨骼畸形。无力型骨病,其BFR低于正常,全段PTH水平稍高、正常或偏低,有明显骨生成不良,骨小梁表面细胞几乎无活性,骨小梁形成和骨吸收均减少,骨小梁进行性变薄。混合性骨病,兼有高周转型骨病、骨软化症两种骨病的特点,其iPTH通常也升高。慢性肾衰竭的其他骨性并发症还包括骨质疏松、透析相关性淀粉样变、转移性钙化等。现就其检测方法综述如下。
出处 《中国医师进修杂志(内科版)》 2008年第8期74-75,共2页 Chinese Journal of Postgraduates of Medicine
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