摘要
目的:研究电针对急性脑梗死大鼠血浆D-二聚体(D-D)及纤维蛋白原(Fib)含量的影响。方法:采用线栓法阻塞大脑中动脉建立局灶性脑缺血模型,40只SD大鼠随机分为正常组、假手术组、模型组、模型电针组,每组10只,采用ELISA法检测各组大鼠血浆D-二聚体含量,用凝固法测定Fib含量。结果:与正常组及假手术组比较,急性脑梗死大鼠血浆D-二聚体、Fib含量均显著升高(P<0.01);与模型组比较,模型电针组大鼠血浆D-二聚体、Fib含量明显降低(P<0.01)。结论:电针能显著降低急性脑梗死大鼠血浆D-二聚体、Fib含量,降低血液黏稠度,改善脑部血液循环。
Objective： To observe the influence of electro - acupuncture （EA） on D - dimer （ D - D ） and Fibrlnogen （Fib） in rats with acute cerebral infarction. Methods ：The acute cerebral infarction rat model was established by using an intraluminal thread blocking the arteria cerebri media. Rats were randomly divided into normal group（ n = 10）, sham - operated group（n = 10） ,model group（n = 10） ,EA group（n = 10）. The contents of D- D and Fib were detected in each group. Results ： Compared with the normal and sham - operation group,the contents of D - D and Fib in model group signif-icantly increased （P 〈 0. 01 ）. Compared with the model group, the contents of D - D and Fib in EA group significantly decreased （ P 〈 0.01 ）. Conclusion ： EA can effectively decrease the contents of D - dimer（ D - D） and Fibrinogen （Fib） in rats with acute cerebral infarction and improve the abnormal of fibrinolysis.
出处
《中华中医药学刊》
CAS
2008年第8期1764-1765,共2页
Chinese Archives of Traditional Chinese Medicine
基金
湖北省教育厅科学研究计划项目(D200516006)
湖北中医学院院级科研资助项目
关键词
急性脑梗死
电针
D-二聚体
纤维蛋白原
cerebral infarction
electro - acupuncture
d - dimer
fibrinogen
