摘要
【目的】对新生儿先天性甲状腺功能低下症(congenital hypothyroidism,CH)筛查确诊的患儿进行评估,以了解上海地区CH筛查的效果。【方法】以25%的比例随机抽取经筛查确诊并坚持治疗随访的40例CH患儿,参考上海市儿童健康检查记录,对每个儿童进行体格发育及精神和动作发育的检查。【结果】40例患儿以年龄评价体重、以年龄评价身高及以身高评价体重与正常标准呈高度相关;不同年龄段的平均智商为101.36±11.57,无智力迟缓者。【结论】通过新生儿疾病筛查,早期诊断及治疗后,CH可以避免体格和智力的障碍;上海地区的CH筛查是有效果的;开展新生儿疾病筛查对提高我国人口素质有重要作用。
[Objective] Children with congenital hypothyroidism （CH） who confirmed by newborn screening were evaluated to understand the effectiveness of CH screening in Shanghai. [Methods] 40 children with CH were selected （25 % of the total children, who had been diagnosed as CH and treated regularly） and referred to the healthcare situation of the children in Shanghai region. The development situation, including weight, height were tested for each children; and also physiological and action development were evaluated. [Results] There was high relationship when it came to the evaluation of weight based on age, height based on age, height based on weight between research group and standards. The average intelligence quotient （IQ） was 101.36 ± 11.57 for children with different age, and no mentality retard was found. [Conclusions] Through newborn screening, the handicap of growth and IQ in children with CH can be avoided after early diagnostics and early treatment. Newborn screening in Shanghai is effective and plays an important role in decreasing congenital defects and enhancing population quality.
出处
《中国儿童保健杂志》
CAS
2008年第4期461-462,共2页
Chinese Journal of Child Health Care
