丹红注射液联合前列环素E_1治疗下肢动脉硬化闭塞症疗效观察被引量：8

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摘要目的观察丹红注射液联合前列环素E1(PGE1)治疗下肢动脉硬化闭塞症的疗效和不良反应。方法58例患者随机分为两组,治疗组应用丹红注射液和PGE1治疗,对照组应用PGE1治疗,比较治疗前后临床疗效,实验室指标如纤维蛋白原、全血黏度、血浆黏度和血细胞沉降率,以及下肢动脉超声检测参数的变化。结果两组治疗后总有效率比较差异无统计学意义,但治疗组显效率(53.3%)明显高于对照组(28.6%),差异有统计学意义(P<0.05);治疗组的阻力指数、全血黏度、纤维蛋白原明显降低,下肢动脉血流量明显增加,与对照组比较均有统计学意义(P<0.05)。两组均未见明显不良反应。结论丹红注射液联合前列环素E1治疗下肢动脉硬化闭塞症疗效显著而且安全,且两药联用效果优于单一用药。

作者李峰刘凤芹唐勇张华芳

机构地区山东省潍坊市人民医院

出处《中西医结合心脑血管病杂志》 2008年第8期987-988,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

关键词下肢动脉硬化闭塞症丹红注射液前列环素E1

分类号 R654.4 [医药卫生—外科学]

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