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阿替普酶与瑞替普酶治疗急性心肌梗死的疗效比较 被引量:13

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摘要 目的:比较阿替普酶(rt-PA)和瑞替普酶(r-PA)治疗急性心肌梗死(AMI)的临床疗效。方法:35例AMI患者分为rt-PA组和r-PA组,分别使用rt-PA全量加速给药或r-PA静脉推注治疗,统计两组胸痛至溶栓时间、再通率、出院前病死率、治疗后并发症及再灌注心律失常发生率。结果:溶栓后,rt-PA组患者血管再通率84.6%,病死率7.7%,出血率0%,再灌注心律失常发生率15.4%。r-PA组患者血管再通率90.9%,病死率9.1%,出血率9.1%,再灌注心律失常发生率13.6%。两组比较差异均无显著性(P>0.05)。结论:rt-PA或r-PA治疗AMI疗效相当。
出处 《实用医学杂志》 CAS 2008年第15期2675-2676,共2页 The Journal of Practical Medicine
基金 2004年广州市属高校科技项目(编号:1054)
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  • 1[1]Reimer KA,Jenning RB.The "wave-front phenomenon" of ischemic cell death,II:transmural progress of necrosis within the framework of ischemic bed size(myocardium at risk)and collateral flow[J].Lab invest,1979,40(6):633-644.
  • 2[2]Linderer T,Schroder R.Prehospital thrombolysis:beneficial effects of very earlyTreatment on infarct size and left ventriculai function[J].JACC,1993,22(5):1304-1310.
  • 3[3]Weaver WD,Cerqueira M,Hallstrom AP,et al.Prehospital-initiated vs hospital-intiated thrombolytic therapy:the myocardial infarction triage and intervention trial[J].JAMA,1993,270(10):1211-1216.
  • 4[4]FTT Collaborative Group.Indications for fibrinolytic therapy in suspected acute myocardial infarctionL collaborative overview of early mortality and morbidity esults from all randomized trials of more than 1000 patients[J].Lancet,1994,343(8893):311-322.
  • 5[5]Chareon P,Gibbons R J.The impact of onset to thrombolytic treatment on outcome in patients with acute myocardial infarction[J].Heart,2000,84(2):142-148.
  • 6[6]Lamfers EJ,Hooghoudt TE,Uppelschoten A,et al.Effect of prehospital thormbolysis on aborting acute myocardial infarction[J].Am J Cardiol,1999,84(8):928-930.
  • 7[7]Benger JR,Karlsten R.Prehospital thrombolysis :lessons from Sweden and their application to the united kingdom[J].Emerg Med J,2002,19(6):578-583.
  • 8[8]Morrow DA,Antman EM.Evaluation of the time saved by prehospital initiation of reteplase for ST-elevation myocardial infarction:results of the Early Retavase-Thrombolysis in Myocardial Infarction(er-timi)19 Trial[J].J Am Cardiol,2002,40(1):71-77.
  • 9[9]The european myocardial infarction project group.Prehospital thrombolystic therapy in patients with suspected acute myocardial infarction[J].N Engl J Med,1993,329(6):383-389.
  • 10[10]Rawles J.Halving of mortality at 1 year by domiciliary thrombolysis in the grampian region EARLY anistreplase trial(GREAT)[J].J Am Coll Cardiol,1994,23(1):1-5.

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