摘要
目的观察益心饮对冠心病(CHD)患者经皮冠状动脉介入治疗(PCI)术后左心室收缩功能的影响。方法将接受PCI术治疗的60例冠心病患者随机分为治疗组和对照组,每组30例。对照组术后予常规西药治疗,治疗组在西药治疗基础上,加服益心饮,两组疗程均为6个月。分别于术前、术后3个月和6个月用彩色多普勒超声心动图检测左心室收缩功能指标和室壁运动情况。结果治疗组术后3个月和两组术后6个月的左室射血分数(LVEF)、左室短轴缩短率(FS)、室间隔收缩幅度(IVSae)及左室后壁收缩幅度(LVPWae)与术前比较均有显著性改善(P<0.05,P<0.01);两组术后6个月LVEF、FS、IVSae、LVPWae指标进行对比,治疗组均显著高于对照组(P<0.05),而室壁运动异常率(WMSD)低于对照组(P<0.05)。结论益心饮能有效改善冠心病PCI术后左心室收缩功能。
Objective To observe the clinical effects of ＂Yixin Decoction＂ on loft ventricle systolic function in patients with coronary heart disease （CHD） after percutaneous coronary intervention （PCI）. Methods Sixty CHD patients who underwent PCI were randomly divided into control group （n=30） received conventional treatment after PCI operation, and treatment group （n=30） received ＂Yixin Decoction＂ plus the conventional treatment. The left ventricular systolic functions and ventricular movement were measured with Doppler echocardiography before operation, 3 months and 6 months after the operation. Results Compared with pre-operation, the left ventricular ejection fraction （LVEF）, left ventricular fractional shortening （FS）, inter-ventricular septum amplitude of excursion （IVSae） and left ventricular posterior wall amplitude of excursion （LVPWae） in treatment group after 3 months, and both groups after 6 months were greatly improved （P〈 0.05, P〈 0.01）. The LYEF, FS, IVSae and LVPWae in treatment group were more improved than those in control group （P〈0.05）, and the rate of segmental left ventricular wall motion disorder （WMSD） were decreased （P〈0.05）. Conclusion ＂Yixin Decoction＂ may improve the left ventricular systolic functions of the patients after PCI.
出处
《上海中医药杂志》
北大核心
2008年第8期20-22,共3页
Shanghai Journal of Traditional Chinese Medicine
关键词
冠心病
经皮冠状动脉腔内介入治疗
益心饮
左心室收缩功能
Coronary heart disease
percutaneous coronary intervention
＂Yixin Decoction＂
left ventricular systolic function
