摘要
应用丹参和甲氰咪胍对大鼠乙酸胃溃疡治疗30天。结果在溃疡制作后的5、30、126天,丹参组的溃疡指数明显低于甲氰咪胍组和对照组(P<0.01),标记率明显高于甲氰咪胍组和对照组(P<0.01),丹参组30天的溃疡指数与126天的相比差异无显著性。表明丹参有促进溃疡愈合,防止再发的作用,且优于甲氰咪胍,其机理是促进了溃疡边缘胃粘膜细胞的增殖。
Using Dan Shen and Cimetidine to treat acetic acid-induced gastric ulcer in rats for 30 days. The uesults
showed that ulcer index of Dan Shen group was obviously lower than that of the Cimetidine group and the contrast
group (P<0. 01) on the 5th, 30th and 126th day, after making the ulcer. Labeling index of Dan Shen group was
obviously higher than that of the Cimetidine group and the contrast group (P<0. 01). There isn' t difference be
tween the ulcer index of Dan Shen group on 30th day and that on the 126th day. It indicated that Dan Shen can
promote healing of ulcer and restrain the recurrence. This role is better than that of Cimetidine. Its mechanism is
that Dan Shen can promote proliferation of gastric mucosal cells on the edge of the ulcer.
出处
《齐齐哈尔医学院学报》
1997年第3期166-168,共3页
Journal of Qiqihar Medical University
