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超声检测新生儿胼胝体的初步研究 被引量:3

The study of corpus callosum in neonate with ultrasonography
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摘要 目的超声检测比较足月正常新生儿和早产儿胼胝体的长度,探讨胼胝体长度与孕周及出生体重的相关性。方法采用新生儿颅脑超声专用探头对30例足月正常新生儿及50例胎龄小于34周早产儿,于出生后当天在静息或睡眠状态下接受经前囟门矢状位颅脑超声探查,测量胼胝体长度(从膝部至压部),分别计算其与孕周及出生体重的相关性。结果50例早产儿,平均(31.02±2.07)孕周,出生体重(1581.30±366.28)g,出生时的胼胝体长度为(39.16±3.20)mm,其中22例极低出生体重儿,胼胝体长度为(36.99±2.84)mm,28例低出生体重儿,胼胝体长度为(40.86±2.33)mm;早产儿出生时的胼胝体长度与孕周适度相关(r=0.3,P<0.05),与出生体重呈正相关(r=0.63,P<0.001)。同期30例足月儿出生时胼胝体的长度为(43.44±2.20)mm,与早产儿相比差异显著,P<0.001。结论超声检测能比较早产儿与足月儿胼胝体的长度,为早期评价早产儿脑发育状况奠定了基础。 Objective To compare the length of corpus callosum(CC) of normal newborn and premature infants with cranial sonography, and to investigate the relationship of length of CC with gestational weeks and birh weight. Methods Thirty normal newborn and 50 premature infants whose gestational age were less than 34 weeks were enrolled in this study. The sagittal midline cranial sonographic images of CC were obtained through anterior fontanelle, the length of CC was measured from the genu and splenium, then the correlation between length of CC and gestational weeks was analyzed respectively. Results In 50 premature infant, mean gestational weeks were (31.02± 2.07), mean birth weight were (1581.30 ± 366.28) g, length of CC were (39.16± 3.20)mm. 22 of 50 were very low birth weight infant, length of CC were (36.99 ± 2.84)ram, and the rest 28 were low birthweight infants, length of CC were (40.86 ± 2.33)mm. The length of CC was correlated moderately well with gestational age at birth(coefficient correlation, r = 0.3, P 〈 0.05), and positive correlated well with birth weight ( r = 0.63, P 〈 0.01 ). There was significant difference between term infants and premature infants( P 〈 0. 001 ). Conclusion Ultrasonography can compare the difference between length of CC of term infants and premature infants, and provide more information for evaluation of premature infants brain development condition in early time.
出处 《临床超声医学杂志》 2008年第8期541-543,共3页 Journal of Clinical Ultrasound in Medicine
关键词 超声检查 新生儿 胼胝体 Ultrasonography Neonate Corpus callosum
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参考文献3

  • 1Miller SP. Vigneron DB,Henry RG,et al.Serial quantitative diffusion tensor MRI of the premature brain:development in newboms with and sithout injury.J Magn Reson Imaging,2002,16(6):621-632.
  • 2Anderson NG, Laurent 1, Cook N. et al. Growth rate of corpus c'allosum in very premature, infanls. AJNR Am J Neuroradiol. 2005,26(10) :2685 - 2690.
  • 3Anderson NG, Laurent 1, Woedward LJ. et al. Detection of impaired growth of the corpus callosum in prenmture infants. Pediatrics. 2006,118 (3) :951 - 960

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