摘要
参考2005年版《中国药典》进行实验,并对所采用的方法进行方法学验证。常规法5菌种中只有白色念珠菌和黑曲霉菌的回收率大于70%,大肠埃希菌、金黄葡萄球菌、枯草芽孢杆菌的回收率均小于70%。而薄膜过滤法回收率均大于70%。结论为薄膜过滤法能有效地去除头孢呋辛酯片的抑菌活性,用该法进行微生物限度检查可行性强,能达到检测的目的。
The article introduces the experiment which reference to the 2005 version of ＂Chinese Pharmacopoeia＂ and verifies the methods. 5 kinds ofbacterias in the conventional method which only aspergillus and candida albicans recovery rate more than 70 percent. Escherichia coli,staphylococcus aureus and bacillus subtilis＇s recovery rate less than 70 percent. The film filtration＇s recovery more than70 percent. The conclusion shows that the film filter can effectively remove cefuroxime axetil tablets antibacterial activity.It uses the law to check the feasibility-microbial limits to achieve the purpose of detection.
出处
《重庆科技学院学报（自然科学版）》
CAS
2008年第4期71-73,共3页
Journal of Chongqing University of Science and Technology：Natural Sciences Edition
关键词
微生物限度检查法
菌数测定
薄膜过滤法
回收率
microbial limits test
determination of the number of bacteria
membrane filtration
recovery
