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树突状细胞疫苗治疗胰腺癌进展 被引量:1

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摘要 胰腺癌的发病率呈明显升高的趋势,外科手术切除率仅为10%~15%,对传统放化疗不敏感,5年生存率低于5%,因此以提高胰腺癌总体疗效为目的的规范化综合治疗成为临床研究的重要问题。树突状细胞(dendritic cell,DC)是目前发现功能最强的专职抗原呈递细胞(antigenpresenting cell,APC),是机体免疫应答的始动者,在诱导、调节、维持机体抗肿瘤免疫中起核心作用。DC疫苗用于抗肿瘤免疫治疗日益受到重视。本文就DC的生物学特性、DC疫苗以及在治疗胰腺癌方面所取得的进展做一综述。
出处 《中华胰腺病杂志》 CAS 2008年第4期282-284,共3页 Chinese Journal of Pancreatology
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