[Objective] Through researching on iodine-deficiency patients who take iodine and healthy people who don＇t take iodine respectively in iodine-deficiency area, to analyze whether there is relative relationship between urinary iodine and urinary fluoride in urine. [Methods] Took 26 people with simple goiter or with cretinism as experimental group and 24 healthy people as control group, measured their urinary iodine and urinary fluoride. [Results ] The average of urinary iodine of experimental group and control group was （126.5±25.8） μg/L and （87.1 ±27.1 ）μg/L. P 〈 0.01 respectively, while the average of urinary fluoride was （0.37±0.11） mg/L and （0.57±0.13） mg/L respectively. The correlation coefficient of urinary iodine and urinary fluoride was r=-0.723. [Conclusions] The average level of urinary iodine of people with simple goiter or with cretinism who take iodine is higher than healthy people who don＇t take iodine, however, as for urinary fluoride, the average level of which of people with simple goiter or with cretinsm taking iodine is lower than healthy people without taking iodine. So it indicates that urinary iodine and urinary fluoride negatively correlate to each other. From this result, we conclude there is competition between urinary iodine and urinary fluoride when they are discharged in human.
Modern Preventive Medicine